Community-Acquired Pneumonia Caused By Haemophilus Influenzae in a Group of Non-Vaccinated Adult Population in Egypt

Community-acquired pneumonia is a common disease and a frequent cause of morbidity and mortality worldwide. Haemophilus influenzae is a leading cause of CAP. The current study was conducted to determine the serotype distribution and antimicrobial susceptibility patterns of Haemophilus influenzae isolated from unvaccinated adult patients with CAP at Assiut University Hospitals. Materials and Methods: From September 2013 to august 2014, sputum samples from 132 adult patients with CAP were analyzed for the detection of Haemophilus influenza using conventional methods. Antimicrobial susceptibility and serotyping of Haemophilus influenzae was performed. Results: Haemophilus influenzae were detected in 21(16%) CAPpatients. Nontypeable H influenzae were the most frequently isolated serotype that found in 15 (71%) of H influenzae-cases. H influenzae type b was found in 5 (24%) cases. While H influenzae type f was found in one (5%) case. Cases were detected mainly during January, February, and March. Resistance was highest for the B-lactam group of antibiotics. Conclusion: CAP has a disease burden in adult patients at Assiut University Hospitals, Egypt. H influenzae is a leading cause of CAP which was associated mostly with non-typeable serotypes. Resistance to penicillin and other antimicrobial agents increased rapidly during the last years among H influenzae strains.